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Response Factor

Although flame ionization detector response is generally proportional to the mass of carbon present in a sample, hetero atoms and various functional groups affect the response to varying degrees. This program will predict response factors from molecular structure. The predictions are based on the multi-linear correlation equation originally developed for a set of some 150 individual structures and has been further refined to account for constitutional, topological and electrostatic properties. The program utilizes four standard formats including: MDL Molefiles, Hyperchem's HIN, SYBOL MOL and MOPAC/AMPAC output file format. (Requires Windows 3.1, 95, 98 or NT and a program that generates one of the above file formats such as Molecular Modeling Pro).


 

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