& TWC BioSearch

There is no better technology for the production of monoclonal antibodies.

ACUSYST improves upon conventional hollow fiber technology with our patented Extracapillary Space Cycling.

The A CU S YST- XCELL ^® incorporates sophisticated process automation and user-friendly, validatable processes for large-scale production (60 -200 grams per month) of monoclonal antibodies.

The A CU S YST- MAXIMIZER ^® is ideal for pilot scale production, capable of producing up to 30 grams per month of mammalian cell secreted proteins.

Designed as an research tool, the A CU S YST- miniMAX ™ mamalian cell culture system is ideal for process optimization or production of less than 10 grams per month of secreted antibody.

Productivity - Cultures That Last
Our goal is to assure that our clients obtain the results they are looking for which usually involves optimizing productivity. The patented cycling process of A CU S YST technology lets operators increase production over conventional systems. In fact, many of our clients have had cultures last well beyond the typical 60 to 90 days. We will assist every step of the way to assure that you get the most out of your cell line.

Consistency - From Run to Run consistency - from run to run

Validation issues are becoming a greater concern as clients address the regulatory requirements of production. We have addressed many of these issues with the design of A CU S YST consistency - from run to run
by automation providing validated software, reliable system operation, and automatic process documentation. In addition, the preassembled, pre-sterilized cultureware not only minimizes the risk of contamination, but is certified for use in your production runs.

Cost - More to Consider consistency - from run to run

When it comes to the production of monoclonal antibodies there is no better alternative than hollow fiber technology- it fosters the production of greater than mg/ml concentrations of antibody, reduces the requirements for high molecular weight (and usually high cost) components, and minimizes the downstream processing costs. ACUSYST consistency - from run to run
takes this a step further by optimizing productivity, minimizing labor requirements, and supporting long term runs.

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TWC Biosearch International
Fax : 2635-0379
Tel (Sales): 2649-9988
Tel (Technical Support)
Email: support@twcbiosearch.com or twcbio@msn.com

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